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Meth & HIV/AIDS

One of the ways Meth changes the brain is the increased chance of violence in users.  There can be dating violence like rapes and sexual assaults - increasing the odds of spreading HIV and other diseases.  People who choose to put themselves in an environment where Meth is used, whether they are using or not, can be putting themselves in danger.  

Meth Opens Path for AIDS
in Users’ Bodies

Scientists have long known that Meth use creates a kind of euphoria that can lead to increased risky behavior and contribute to the spread of HIV infection.  Now, researchers have shown a second way that Meth increases the risk of infection and can speed up the pace of the disease. It is at the level of the virus interacting with the cells of the body, at the same juncture that is responsible for the pleasurable effects of Meth. 
A cellular biologist at the University at Buffalo examined a part of the immune system (dendritic cells) that the HIV virus initially latches onto when entering a body.  He followed the action of Meth as it attached itself to dopamine receptors on cells.  The drug somehow forces the creation of more of a specific molecule that HIV grabs on to near the surface of the skin.  Then, the cells with the HIV attached travels deeper into the immune system.  The sheer number of virus molecules attached to the Meth-activated dendritc cells overwhelms the natural defensive cells (T-cells) of the human body.

The study was published online on Aug. 4, 2006 in the Journal of Neuroimmune Pharmacology (Article no longer available online).

Meth use increases risk of HIV/AIDS in a number of other ways.  

Risk factors for Meth use can include sexual risk factors. Several studies demonstrate that Meth users are more likely to engage in risky sex acts than non-users. Such behaviors can include sex with multiple and/or anonymous partners, unprotected sex and “sex marathons.” Meth use reportedly increases sex drive while over time also reduces sexual pleasure and/or causes impotence.

Also, Meth users who inject the drug frequently share needles. In one California study, 1/3 of Meth users used needles. Among needle-users, 47% had shared and/or borrowed needles. Law enforcement in some areas of South Dakota report that much higher than 1/3 of Meth users are injecting.  Law enforcement in Rapid City, for example, reported as a “majority” of Meth users in the area are using needles.  

Limited studies have also shown that independent of other risk factors, Meth users appear more likely to become infected with the HIV virus, and carry higher viral loads.  Reasons for this are still unknown, but could possibly be attributed to lowered immune resistance in Meth users (due to the drug or lifestyle factors like lack of sleep or poor nutrition), dried-out mucous membranes in the vagina, anus and/or mouth along with longer duration of sex contributing to possible tearing of tissue increasing risk of transmission.

Among heterosexual people and men who had sex with men (MSM), Meth users:

  • reported more sex partners

  • were less likely to report condom use

  • were two-times more likely to report sex in exchange for money or drugs,

  • were four-times as likely to report having sex with an injection-drug user

  • had a strong history of a sexually transmitted disease (STD)

Sources include:
SD Department of Health statistics from South Dakota Epidemiologic

Profile of HIV/AIDS 2007
Molitor F, Traux SR, Ruiz JD, Sun RK.  “Association of Methamphetamine use during sex with risky sexual behaviors and HIV infection among non-injection drug users.” West J Med 1998; 168:93—7.



                             

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